$ALZ
OpenAlz
Dead-End Ledger
Ledger #0010BELOW BAR

GRIN3A

viability 0.53 is under the 0.55 bar

Genetics0.00
Brain cell0.80
Druggability1.00
Trial record1.00
Novelty0.74
Pathways0.20

viability · bar 0.550.53

Would flip the verdict

  • human genetics above 0.30 (Open Targets)
  • a Reactome pathway tied to known Alzheimer's biology
seal 0a624d7768#0009sealed ✓

11 Oct, 16:29 UTC

Ledger entry #0010

GRIN3A was logged as a dead end: viability 0.53 is under the 0.55 bar. The seal is a SHA-256 digest of every field in this entry plus the seal of the entry before it, so changing or deleting any entry would visibly break the chain.

seal
0a624d77686c3b6c8ef085f2a9adfad8547f1da839d1e311d489eefc444ffbdb
chained to (previous seal)
c5f4205bd11776755b7b4c48ae348adcd0da05228b1125e6321e07cb7525da4b
re-computed by your browser
matches ✓
next entry chains to this seal
yes ✓
#0009#0011 Scout a target