$ALZ
OpenAlz
Dead-End Ledger
Ledger #0012BELOW BAR

CDC25B

viability 0.45 is under the 0.55 bar

Genetics0.00
Brain cell0.50
Druggability0.70
Trial record1.00
Novelty0.83
Pathways0.20

viability · bar 0.550.45

Would flip the verdict

  • human genetics above 0.30 (Open Targets)
  • a Reactome pathway tied to known Alzheimer's biology
seal 4123b35d97#0011sealed ✓

11 Oct, 16:36 UTC

Ledger entry #0012

CDC25B was logged as a dead end: viability 0.45 is under the 0.55 bar. The seal is a SHA-256 digest of every field in this entry plus the seal of the entry before it, so changing or deleting any entry would visibly break the chain.

seal
4123b35d970dd8fc74e4ffa1cbf14ae53c7819c2d28588e2970c3347f3e6dbd9
chained to (previous seal)
f21cf3306e26289728186016c65d9161eeb6397f0467c39be069756c65459311
re-computed by your browser
matches ✓
next entry chains to this seal
yes ✓
#0011#0013 Scout a target