$ALZ
Dead-End Ledger
Ledger #0002BELOW BAR

PSEN2

viability 0.50 is under the 0.55 bar

Genetics0.20
Brain cell0.50
Druggability0.90
Trial record0.64
Novelty0.19
Pathways1.00

viability · bar 0.550.50

Would flip the verdict

  • human genetics above 0.30 (Open Targets)
seal cbd53f268b#0001sealed ✓

11 Oct, 15:39 UTC

Ledger entry #0002

PSEN2 was logged as a dead end: viability 0.50 is under the 0.55 bar. The seal is a SHA-256 digest of every field in this entry plus the seal of the entry before it, so changing or deleting any entry would visibly break the chain.

seal
cbd53f268b81cfcdaa9a247ed5e2887562d923fd3adc486a63bc792414345df4
chained to (previous seal)
f31956d37e372ced6d7c036d0c62e97389c8b3b6a20a136084d5eac73c2aa6e6
re-computed by your browser
matches ✓
next entry chains to this seal
yes ✓