PSAP
viability 0.46 is under the 0.55 bar
Genetics0.00
Brain cell0.50
Druggability0.70
Trial record1.00
Novelty0.60
Pathways0.55
viability · bar 0.550.46
Would flip the verdict
- human genetics above 0.30 (Open Targets)
11 Oct, 16:54 UTC
Target Scout
Scout a target.
Six live evidence lines, one viability index, and either an experiment card with a kill criterion or a sealed Dead-End Ledger entry. Runs on public data alone, so it never hits capacity.
37 targets scouted · 37 in the last 24h · 43 experiment cards · 16 dead ends logged
Quick picks
Genetics
Open Targets
—
Brain cell
Human Protein Atlas
—
Druggability
Open Targets
—
Trial record
ClinicalTrials.gov
—
Novelty
PubMed
—
Pathways
Reactome
—
Target Scout grades a gene on six independent evidence lines pulled live from public databases. Clear the 0.55 viability bar and you get an experiment card with a kill criterion. Fall short and the reason is sealed into the Dead-End Ledger.
Live nowwaiting for the next scout
- PSAPBrain cell · querying HPA brain single-nuclei atlas4m ago
- PSAPBrain cell · no CNS home. low cell type specificity4m ago
- PSAPDruggability · querying Open Targets tractability4m ago
- PSAPDruggability · tractability 0.70: high-quality pocket.4m ago
- PSAPTrial record · querying ClinicalTrials.gov4m ago
- PSAPTrial record · 0 Alzheimer's trial(s).4m ago
- PSAPNovelty · querying PubMed4m ago
- PSAPNovelty · 24 with Alzheimer's / 712 total. novelty 0.60.4m ago
- PSAPPathways · querying Reactome4m ago
- PSAPPathways · 5 pathway(s), mostly immune signalling.4m ago
- PSAPviability index 0.46 against a bar of 0.55 · fingerprint c5570e4bb00f4m ago
- PSAPPSAP: viability 0.46 is under the 0.55 bar. logged as ledger entry #16. #00164m ago
Scout board
- rank 10.83
PLCG2 · microglia
phospholipase C gamma 2 · scouted 29m ago
Genetics0.91Brain cell1.00Druggability0.60Trial record1.00Novelty0.49Pathways1.00 - rank 20.82
CD33 · microglia
CD33 molecule · scouted 44m ago
Genetics0.84Brain cell1.00Druggability0.90Trial record0.96Novelty0.31Pathways1.00 - rank 30.79
APH1B · neurons
aph-1B gamma-secretase subunit · scouted 57m ago
Genetics0.89Brain cell0.50Druggability0.90Trial record1.00Novelty0.52Pathways1.00 - rank 40.78
APOC1 · microglia
apolipoprotein C1 · scouted 10m ago
Genetics0.90Brain cell1.00Druggability0.30Trial record1.00Novelty0.42Pathways1.00 - rank 50.75
TREM2 · microglia
triggering receptor expressed on myeloid cells 2 · scouted 50m ago
Genetics0.92Brain cell1.00Druggability0.60Trial record0.80Novelty0.09Pathways1.00 - rank 60.73
CR1 · oligodendrocytes
complement C3b/C4b receptor 1 (Knops blood group) · scouted 19m ago
Genetics0.93Brain cell0.80Druggability0.30Trial record0.98Novelty0.29Pathways1.00 - rank 70.71
NCK2 · microglia
NCK adaptor protein 2 · scouted 16m ago
Genetics0.86Brain cell0.80Druggability0.60Trial record1.00Novelty0.74Pathways0.20 - rank 80.70
PSEN1 · oligodendrocytes
presenilin 1 · scouted 1h ago
Genetics0.82Brain cell0.80Druggability0.90Trial record0.50Novelty0.09Pathways1.00 - rank 90.68
CLU · astrocytes
clusterin · scouted 1h ago
Genetics0.73Brain cell0.80Druggability0.50Trial record0.92Novelty0.25Pathways1.00 - rank 100.68
ADAM10 · neurons
ADAM metallopeptidase domain 10 · scouted 1h ago
Genetics0.81Brain cell0.50Druggability0.70Trial record0.96Novelty0.20Pathways1.00 - rank 110.67
GRN · microglia
granulin precursor · scouted 54m ago
Genetics0.81Brain cell0.80Druggability0.70Trial record0.90Novelty0.27Pathways0.55 - rank 120.67
SORL1 · microglia
sortilin related receptor 1 · scouted 1h ago
Genetics0.76Brain cell1.00Druggability0.50Trial record0.96Novelty0.27Pathways0.55
Recently scoutedPSAP 0.46MS4A6A 0.66MS4A6A 0.66ADRA2B 0.56ADRA2B 0.56APOC1 0.78APOC1 0.78FOXO3 0.44
Dead-End Ledger
16 dead ends logged 9/9 latest seals re-verified by your browser 8/8 chain links intactopen the ledger →
FOXO3
viability 0.44 is under the 0.55 bar
Genetics0.00
Brain cell0.50
Druggability0.60
Trial record1.00
Novelty0.53
Pathways0.55
viability · bar 0.550.44
Would flip the verdict
- human genetics above 0.30 (Open Targets)
11 Oct, 16:45 UTC
FOXO3
viability 0.44 is under the 0.55 bar
Genetics0.00
Brain cell0.50
Druggability0.60
Trial record1.00
Novelty0.53
Pathways0.55
viability · bar 0.550.44
Would flip the verdict
- human genetics above 0.30 (Open Targets)
11 Oct, 16:43 UTC
HMGCR
viability 0.43 is under the 0.55 bar
Genetics0.00
Brain cell0.50
Druggability1.00
Trial record0.96
Novelty0.49
Pathways0.20
viability · bar 0.550.43
Would flip the verdict
- human genetics above 0.30 (Open Targets)
- a Reactome pathway tied to known Alzheimer's biology
11 Oct, 16:43 UTC
CDC25B
viability 0.45 is under the 0.55 bar
Genetics0.00
Brain cell0.50
Druggability0.70
Trial record1.00
Novelty0.83
Pathways0.20
viability · bar 0.550.45
Would flip the verdict
- human genetics above 0.30 (Open Targets)
- a Reactome pathway tied to known Alzheimer's biology
11 Oct, 16:36 UTC
HFE
viability 0.48 is under the 0.55 bar
Genetics0.61
Brain cell0.35
Druggability0.50
Trial record0.20
Novelty0.49
Pathways0.55
viability · bar 0.550.48
Would flip the verdict
- enrichment in a brain cell type we can culture
11 Oct, 16:33 UTC
GRIN3A
viability 0.53 is under the 0.55 bar
Genetics0.00
Brain cell0.80
Druggability1.00
Trial record1.00
Novelty0.74
Pathways0.20
viability · bar 0.550.53
Would flip the verdict
- human genetics above 0.30 (Open Targets)
- a Reactome pathway tied to known Alzheimer's biology
11 Oct, 16:29 UTC
CDK5R1
viability 0.42 is under the 0.55 bar
Genetics0.00
Brain cell0.50
Druggability0.70
Trial record1.00
Novelty0.65
Pathways0.20
viability · bar 0.550.42
Would flip the verdict
- human genetics above 0.30 (Open Targets)
- a Reactome pathway tied to known Alzheimer's biology
11 Oct, 16:24 UTC
SLC6A3
viability 0.48 is under the 0.55 bar
Genetics0.00
Brain cell0.00
Druggability1.00
Trial record0.94
Novelty0.63
Pathways1.00
viability · bar 0.550.48
Would flip the verdict
- human genetics above 0.30 (Open Targets)
- enrichment in a brain cell type we can culture
11 Oct, 16:18 UTC